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Joined 1 year ago
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Cake day: June 1st, 2025

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  • Can you find me a source that says that Doxypep is efficent for HIV? Because as i said HIV is a virus and antibiotics typically only work on bacteria… To be exact they block the 30s ribosomal subunit, HIV does not have that.
    And please do not downtalk me and assume some shit about my land of origin or education. That is very unfriendly.





  • I am against AI and LLMs but the reason is quite simple, a lot of modern writing is offical bullshit to get stuff approved. Research grants, medical therapy approval, offical work mail that has to sound professional, job applications (insofar that noone cares what you write, they want a standard template and pick a candidate along qualifications anyways.). All these texts cost a lot of time and it makes no difference if a human or some copy machine writes it. And tbh. were it not for all the disadvantages of modern LLMs i would use it for the exact same reason, because sitting at a grant application for two hours while others do it in 5min is fucking useless and exhausting.







  • Contact info gets hashed in a clever way which doesn’t send your info (although i guess phone number hashes could be brute forced?) Meta data is also not available. They have no way to know who you are talking to. The only info they have is that you logged ij with a ip at a time. I believe they can’t even reliable track how many messages you send. Even with a compromised server most of the magic happens in the open source client side app so that they can’t gather very much. I understand your concerns about popular centralized services but i really believe that they are unfound with signal.



  • Can’t read the whole article due to paywall. Here are 2 thoughts for the half that i did read.

    • colorectal cancer makes a lot of sense as a target. it still is one of the most cancers with the highest mortality. At the same time we saw an uptick in colorectal cancer rates in young people (reason unknown, maybe microplastics maybe something else.). Furthemore colorectal cancer seems to be a great target for immunsystem modulating therapy. There was a paper 3 years bake in I think the NEJM where they put 18/18 (exact N not sure) patients in remission with PD-1 modulation which also activates the immun system.

    • Astra Zeneca (I believe) is also working on a mRNA vaccine for cancer that is quite far along. They are targeting melanoma in remission and reduced reoccurence of melanoma or metastasis after 3 years by 50%. So it seems like mRNA cancer vaccines will be a strong pillar for future cancer treatements.

    Sadly we saw in the past that russia sometimes bolsters their numbers for medication efficency. I hope it is not the case this time but i hope that the phase 2/3 trials will be very transparent to quench any doubts.